In Splice, two scientists mix the DNA of several creatures to create a hybrid. It's part human, part...um, it's got wings and three fingers and a stinger tail and weird legs, so who knows. Director Vicenzo Natali has also mixed DNA from different filmmakers and genres to create this bizarre hybrid of a movie: part sci-fi, part horror, part Cronenberg gross-out. Usually, mixes like this end up like Dren, the creature creation in this film: a nightmarish mess. Surprisingly, this film is really, really good.
It starts with two very talented actors in Adrian Brody and Sarah Polley as the couple, both in science and romance. They are genetic engineers who create weird creatures whose proteins cure disease. They take things too far when they add human DNA to their experiments and create Dren. She (it?) starts out as a strange blob that Brody's Clive thinks they should kill off (it's a crazy genetic creation, and in movies, they always end up doing horrible things), but as she/it grow (at an accelerated rate), it starts to look more human, and Polley's Elsa, who had a horrible childhood and never wanted children of her own, starts to treat Dren like her own daughter. Meanwhile, Clive and Dren's relationship breport this review for TOS violationes, well, morereport this review for TOS violationplicated.
This film has a lot to say about tampering in God's domain, which has been debated in cinema since the art form began. But Splice takes things in weird directions that kept me surprised for most of the film. The main thing that separates this film from others that are less successful is itsreport this review for TOS violationmitment. Whatever direction it's going in, it goes there 100%. It's creepily sexy, almost stomach churningly so at times. There's emotional resonance to the scenes between Elsa and Dren. The effects were well done, but didn't detract from the story. The last 15 minutes are a little disappointing, but only because whatreport this review for TOS violationes before it was so intriguing.