A graduate of Towson University's Electronic Media and Film department, he began his feature film career in 2000 with "Makebelieve" at the age of 21. His follow up, "Still Life" (2001) was an award winning digital feature shot in and around Baltimore.
Flanagan then produced television programming for Discovery and ESPN in 2002, and in 2003 wrote and directed the award-winning feature film "Ghosts of Hamilton Street". Later that year, Mike was the Director of Photography for the cult hit "Chainsaw Sally" by Writer/Director Jimmy O Burril.
Mike moved from Baltimore to Los Angeles the day after "Chainsaw Sally" wrapped, and almost immediately found work directing & editing "The Gleib Show" for National Lampoon Networks and several reality television programs, as well as regional commercials.
In 2005, Flanagan turned to the horror genre for the first time with "Oculus", an applauded short film that is just the beginning of an ambitious horror anthology, which eventually became the inspiration for his 2013 feature film of the same name.
In 2010, after raising funds on Kickstarter, he wrote and directed the applauded indie horror film "Absentia," which he credits with establishing his career. "Absentia," shot for 70k in Flanagan's apartment, led to "Oculus" (2014) and "Somnia" (2015).