Michele Santopietro is an American actress of Italian and German descent. She is probably best known for her recurring character JoJo Palmice on HBO's The Sopranos, from seasons 1 through to 4. Santopietro has also had guest lead appearances on television shows such as Law & Order, Law & Order SVU, Sex and the City and the CBS television series New York News.
Santopietro also played one of the lead characters, Laura, in the Lionsgate feature film Two Family House with Michael Rispoli and Kelly MacDonald. She also recently starred opposite Adrian Grenier in the feature film A Perfect Fit, and can be seen opposite Teri Polo and Barry Bostwick in the made for television film Love is a Four Letter Word.
Santopietro stars in The Donner Party, alongside Crispin Glover, Christian Kane, Mark Boone Jr. and Clayne Crawford. The film is based on the historical Donner Party in 1846 and Santopietro plays Amanda McCutcheon. She has also voiced many television and radio commercials as well as video games, audio books, audio dramas, and promotional voice work for television including Discovery's Animal Planet Network and the Lifetime series "Prom Queens."